Enhanced antitubercular activity, alveolar deposition and macrophages uptake of mannosylated stable nanoliposomes
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چکیده
منابع مشابه
Uptake and transport of mannosylated ligands by alveolar macrophages. Studies on ATP-dependent receptor-ligand dissociation.
During endocytosis, mannosylated ligands enter vesicles which have a density intermediate between that of the plasma membrane and secondary lysosomes. Mannosylated ligands are transferred from these vesicles to lysosomes. A solubilization-precipitation assay was used to study the dissociation of mannosylated ligands from their receptor. In whole cells dissociation was rapid (t 1/2 (37 degrees C...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery Science and Technology
سال: 2019
ISSN: 1773-2247
DOI: 10.1016/j.jddst.2019.03.032